Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028721 | 0.86 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL8309798 | 0.84 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL14423542 | 0.83 | ELANE (0.41) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL14423555 | 0.78 | CYP1A2 (0.44) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL7432714 | 0.78 | CYP1A2 (0.44) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL15803985 | 0.77 | GAA (0.45) | L3MBTL1ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL15799353 | 0.76 | GAA (0.42) | L3MBTL1ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL7699724 | 0.76 | ELANE (0.41) | L3MBTL1ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL9899997 | 0.75 | CYP1A2 (0.42) | L3MBTL1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL7284088 | 0.75 | RAD52 (0.50) | L3MBTL1ALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262211-B2 | Aromatic heterocyclic non-covalent inhibitors of urokinase and blood vessel formation | DENDREON CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262211-B2 | Aromatic heterocyclic non-covalent inhibitors of urokinase and blood vessel formation | DENDREON CORPORATION (US) | 2007-08-28 | — | — | US | disclosed |