Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.82 |
| ▸ | DRD3 | P35462 | 3/20 | 0.82 |
| ▸ | DRD2 | P14416 | 14/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 14/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14423678 | 0.94 | ADRB2 (0.82) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL12619839 | 0.92 | ADRB2 (0.81) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL3834258 | 0.89 | ADRB2 (0.98) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL12619844 | 0.88 | ADRB2 (0.82) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL12619790 | 0.87 | ADRB2 (0.80) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1801828 | 0.87 | ADRB2 (0.92) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL1799898 | 0.87 | ADRB2 (0.79) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1801825 | 0.87 | ADRB2 (0.92) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1803538 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL1801823 | 0.85 | ADRB2 (0.92) | ADRB2ADRB1DRD3DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |