Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.92 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.92 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.92 |
| ▸ | DRD2 | P14416 | 11/20 | 0.92 |
| ▸ | DRD3 | P35462 | 3/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801825 | 1.00 | ADRB2 (0.92) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1799537 | 0.96 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1799536 | 0.96 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1802888 | 0.95 | ADRB2 (0.98) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1802887 | 0.95 | ADRB2 (0.98) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL1800656 | 0.93 | ADRB2 (0.81) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1802047 | 0.90 | ADRB2 (0.83) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1796654 | 0.90 | ADRB2 (0.83) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1796656 | 0.90 | ADRB2 (0.83) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1799589 | 0.89 | ADRB2 (0.81) | ADRB2ADRB1ADRA1DDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | claimed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | claimed |
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-7951954-B2 | Bezothiazol derivatives as Beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2011-05-31 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ASTRAZENECA AB (SE) | 2009-03-05 | — | — | US | disclosed |
| WO-2007106016-A1 | BEZOTHIAZOL DERIVATIVES AS BETA2 ADRENORECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062259-A1 | Bezothiazol Derivatives as Beta2 Adrenoreceptor Agonists | ADRB2, ADRB1, ADRB3 | ADRB2 1/4885ADRB1 2/4885ADRA1D 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.