Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24885803 | 0.87 | POLB (0.56) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL30078219 | 0.87 | POLB (0.56) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL31290976 | 0.85 | CA12 (0.68) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL3488219 | 0.85 | CA12 (0.68) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL6239637 | 0.84 | POLB (0.58) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL29592689 | 0.83 | POLB (0.52) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL2249264 | 0.83 | POLB (0.52) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL30100149 | 0.83 | MAOA (0.67) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL654558 | 0.83 | MAOA (0.67) | CA12CA9POLBMAOBMAOA | |
| SCHEMBL4001852 | 0.83 | POLB (0.69) | CA12CA9POLBMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262318-B2 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER, INC. (US) | 2007-08-28 | — | — | US | disclosed |