SCHEMBL2249264

SCHEMBL2249264

CCOC(=O)c1cc2cc([N+](=O)[O-])ccc2o1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
MAOB P27338 3/20 0.50
MAOA P21397 2/20 0.50
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
USP2 O75604 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
KMT2A Q03164 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29592689 1.00 POLB (0.52) POLBCA12CA9MAOBMAOA
SCHEMBL6509784 0.90 SMN1; SMN2 (0.49) MAOBSMN1; SMN2MAPTKDM4EALDH1A1
SCHEMBL27491194 0.85 CA12 (0.48) POLBCA12CA9MAOBMAOA
SCHEMBL655464 0.85 CA12 (0.56) POLBCA12CA9MAOBMAOA
SCHEMBL4253620 0.84 MAOB (0.66) CA12CA9MAOBSMN1; SMN2MAPT
SCHEMBL7672880 0.84 CA12 (0.69) POLBCA12CA9MAOBMAOA
SCHEMBL30595105 0.84 CA12 (0.69) POLBCA12CA9MAOBMAOA
SCHEMBL14423946 0.83 CA12 (0.57) POLBCA12CA9MAOBMAOA
SCHEMBL16732780 0.82 CA12 (0.46) POLBCA12CA9MAOBMAOA
SCHEMBL16943491 0.82 CA12 (0.52) POLBCA12CA9MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119143705-A Benzofuran lymph specific tyrosine phosphatase inhibitor and preparation method and application thereof 山东大学 2024-12-17 CN claimed
CN-118813733-A Biocatalysis method for preparing vilazodone intermediate 广东东阳光药业股份有限公司 2024-10-22 CN claimed
CN-118745163-A Benzofuran compound, preparation method and application thereof, and PDGFR kinase inhibitor 四川省医学科学院·四川省人民医院 2024-10-08 CN claimed
WO-2014061004-A2 PROCESS FOR THE PREPARATION OF VILAZODONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF RANBAXY LABORATORIES LIMITED (IN) 2014-04-24 WO claimed
CN-114401960-B Glue degradation agent and using method thereof NOVARTIS AG (CH) 2026-05-26 CN disclosed
EP-4695240-A2 CYCLIC VINYL SULFONE WRN INHIBITORS Nimbus Wadjet, Inc. (US) 2026-02-18 EP disclosed
US-20260010085-A1 NON-MAGNETIC ONE-COMPONENT DEVELOPING TONER AND METHOD FOR PRODUCING NON-MAGNETIC ONE-COMPONENT DEVELOPING TONER KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2026-01-08 US disclosed
CN-119822964-A Synthesis method of visible light-induced copper-catalyzed diarylamine compound 铜陵学院 2025-04-15 CN disclosed
CN-119504380-A Liquid stabilizer for nitrate compound and preparation method thereof 南京理工大学 2025-02-25 CN disclosed
CN-119462394-A Selective controllable synthesis method of two types of alkyl aromatic amine compounds 铜陵学院 2025-02-18 CN disclosed
EP-3719577-B1 TONER BINDER AND TONER SANYO CHEMICAL IND LTD (JP) 2025-01-01 EP disclosed
CN-119143705-A Benzofuran lymph specific tyrosine phosphatase inhibitor and preparation method and application thereof 山东大学 2024-12-17 CN disclosed
US-20050227986-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2005-10-13 US disclosed
WO-2005080367-A1 EP2 RECEPTOR AGONISTS PHARMAGENE LABORATORIES LIMITED (GB) 2005-09-01 WO disclosed
WO-2005032594-A2 ALKYLATORS LINKED TO POLYAMIDES AS DNA BINDING AGENTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-04-14 WO disclosed
EP-1463714-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS Amgen Inc. (US) 2004-10-06 EP disclosed
US-20030195201-A1 Vanilloid receptor ligands and their use in treatments AMGEN INC. 2003-10-16 US disclosed
WO-2003049702-A2 VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS AMGEN INC. (US) 2003-06-19 WO disclosed
US-5977112-A Process of making substituted benzofurans MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-11-02 US disclosed
US-5723614-A Benzofurans MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195201-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 POLB 3603/4885CA12 1985/4885CA9 1823/4885
US-20050227986-A1 Vanilloid receptor ligands and their use in treatments TRPV1, TRPV2, TRPV3 POLB 3171/4885CA12 2051/4885CA9 1812/4885
US-20260010085-A1 NON-MAGNETIC ONE-COMPONENT DEVELOPING TONER AND METHOD FOR PRODUCING NON-MAGNETIC ONE-COMPONENT DEVELOPING TONER PSMD2, PSMD1, SMC4 POLB 3615/4885CA12 1203/4885CA9 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.