Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247132 | 1.00 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8246003 | 1.00 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL482141 | 0.82 | MEN1 (0.37) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8067270 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL13795024 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL4738730 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL3465697 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL3259183 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL9376106 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8246038 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |
| US-7261995-B2 | Nitrogen-containing organic compound, chemically amplified resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-08-28 | — | — | US | disclosed |