Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424154 | 1.00 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8246003 | 1.00 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL482141 | 0.82 | MEN1 (0.37) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8067270 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL13795024 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL4738730 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL3465697 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL3259183 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL9376106 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 | |
| SCHEMBL8246038 | 0.80 | KDM4E (0.44) | MEN1KMT2ASLC6A4SLC6A3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080154043-A1 | PROCESS FOR THE MANUFACTURE OF 7-OXA-BICYCLO DERIVATIVES | CYP3A7, UGT2B7, CYP1B1 | MEN1 2284/4885KMT2A 4393/4885SLC6A4 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.