SCHEMBL144243

SCHEMBL144243

N#Cc1cc(Br)cc(Br)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 8/20 0.43
GPR35 Q9HC97 2/20 0.41
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 2/20 0.35
XDH P47989 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ABL1 P00519 1/20 0.33
KDR P35968 1/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TTR P02766 1/20 0.32
ALB P02768 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29582221 1.00 ADRB2 (0.43) ADRB2GPR35GAAMAPTHTT
SCHEMBL9478745 0.88 XDH (0.37) ADRB2GPR35GAAMAPTHTT
SCHEMBL10119242 0.82 MAPT (0.56) ADRB2GAAMAPTHTTXDH
SCHEMBL18343829 0.82 XDH (0.34) ADRB2GPR35GAAMAPTHTT
SCHEMBL11436064 0.80 TTR (0.50) ADRB2GPR35GAAMAPTHTT
SCHEMBL3230060 0.78 ADRB2 (0.42) ADRB2GPR35XDHMAOAMAOB
SCHEMBL11040450 0.78 ADRB2 (0.41) ADRB2GAAMAPTHTTXDH
SCHEMBL6119734 0.78 CYP3A4 (0.36) ADRB2GPR35MAPTXDHMAOA
SCHEMBL2656138 0.78 ADRB2 (0.35) ADRB2GPR35XDHMAOAMAOB
SCHEMBL2656947 0.78 TSHR (0.36) ADRB2GPR35MAPTHTTXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110283328-A A kind of zirconium metal-organic framework material and preparation method thereof as crystal sponge 江汉大学 2019-09-27 CN claimed
EP-4643644-A2 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS Syngenta Crop Protection AG (CH) 2025-11-05 EP disclosed
EP-4051673-B1 PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-09-24 EP disclosed
CN-114630825-B Condensed with pesticidal activity bicyclic heteroaromatic compounds 先正达农作物保护股份公司 2025-05-16 CN disclosed
US-12179173-B2 Functionalized porous organic polymers as uranium nano-traps for efficient uranium extraction UNIVERSITY OF SOUTH FLORIDA (US) 2024-12-31 US disclosed
CN-114466850-B [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine 拜耳股份有限公司 2024-09-10 CN disclosed
US-20240109051-A1 FUNCTIONALIZED POROUS ORGANIC POLYMERS AS URANIUM NANO-TRAPS FOR EFFICIENT URANIUM EXTRACTION UNITED STATES DEPARTMENT OF ENERGY 2024-04-04 US disclosed
CN-111263766-B Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device and lighting device 三菱化学株式会社 2024-04-02 CN disclosed
CN-114874189-B Substituted heteroaryl derivatives, compositions and uses thereof 深圳市塔吉瑞生物医药有限公司 2023-09-29 CN disclosed
CN-111867989-B Functionalized porous organic polymers as uranium nanotraps for efficient uranium extraction 南佛罗里达大学 2023-09-26 CN disclosed
US-4157893-A MONO OR DISAZO DYE CONTAINING AN AMINO-SUBSTITUTED PYRIMIDINE RING BASF AKTIENGESELLSCHAFT (DE) 1979-06-12 US disclosed
US-4154577-A Uniformly disperse dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed
US-4150943-A Uniformly dyed water-swellable cellulosic fibers BASF AKTIENGESELLSCHAFT (DE) 1979-04-24 US disclosed
US-4146535-A Azo dyes having a 3-cyano- or 3-carbamoyl-2,6-diamino-pyridine coupling component BASF AKTIENGESELLSCHAFT (DE) 1979-03-27 US disclosed
US-4145341-A WATER-SOLUBLE AZO DYES CONTAINING DIAMINOPYRIMIDINE COUPLER COMPONENTS BASF AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed
US-4083684-A AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE BASF AKTIENGESELLSCHAFT (DT) 1978-04-11 US disclosed
US-4039529-A Cycloaliphatic dicarbonyl containing azo dyestuffs CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4014864-A POLYESTER FIBERS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3987192-A ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID THE UPJOHN COMPANY (US) 1976-10-19 US disclosed
US-3971771-A DYES FOR POLYESTERS CIBA-GEIGY AG (CH) 1976-07-27 US disclosed