Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753516 | 0.87 | — | — | |
| SCHEMBL24595109 | 0.82 | PTGS1 (0.33) | PTGS1PTGS2 | |
| SCHEMBL14424433 | 0.76 | — | — | |
| SCHEMBL12802414 | 0.75 | RAPGEF4 (0.32) | PTGS1PTGS2 | |
| SCHEMBL12955393 | 0.75 | DAO (0.45) | PTGS1PTGS2 | |
| SCHEMBL21728216 | 0.75 | DAO (0.45) | PTGS1PTGS2 | |
| SCHEMBL13913195 | 0.71 | — | — | |
| SCHEMBL13913193 | 0.71 | — | — | |
| SCHEMBL14424431 | 0.71 | — | — | |
| SCHEMBL14424435 | 0.69 | NOS1 (0.33) | PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7255811-B2 | Tolane derivatives and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2007-08-14 | — | — | US | disclosed |