Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14424316 | 0.84 | TRPV1 (0.61) | EPHX2HDAC3HDAC8HDAC6 | |
| SCHEMBL10116639 | 0.77 | PPARA (0.67) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL13947580 | 0.76 | LSS (0.72) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL14424663 | 0.75 | GAA (0.47) | NR1H4HDAC3HDAC8HDAC6 | |
| SCHEMBL3455877 | 0.75 | LSS (0.69) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL4497840 | 0.75 | LSS (0.69) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL20477562 | 0.75 | L3MBTL1 (0.69) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL6572354 | 0.75 | HDAC6 (0.72) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL20477571 | 0.74 | MEN1 (0.73) | LSSEPHX2PPARGPPARAMAPK14 | |
| SCHEMBL3158764 | 0.74 | EPHX2 (0.73) | LSSEPHX2PPARGPPARAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265130-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2007-09-04 | — | — | US | disclosed |