Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425213 | 0.83 | TSHR (0.44) | RXRAMAPTMAPK1GAATSHR | |
| SCHEMBL14425218 | 0.82 | CYP26A1 (0.40) | RXRAMAPK1TSHRCYP26A1CYP26B1 | |
| SCHEMBL28481448 | 0.79 | EGFR (0.42) | GNRHRRXRAMAPTGAACYP26A1 | |
| SCHEMBL17049086 | 0.78 | CYP3A4 (0.51) | RXRAMAPTMAPK1HSD17B10TSHR | |
| SCHEMBL23371572 | 0.76 | CYP26A1 (0.44) | RXRAMAPK1TSHRCYP26A1CYP26B1 | |
| SCHEMBL22836804 | 0.75 | RXRA (0.62) | RXRAMAPK1TSHRCYP26A1CYP26B1 | |
| SCHEMBL23439027 | 0.74 | CYP26A1 (0.46) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL24562676 | 0.74 | RXRA (0.42) | RXRAGAACYP26A1CYP26B1RARA | |
| SCHEMBL23927691 | 0.73 | RXRA (0.41) | RXRACYP26A1CYP26B1RARARARB | |
| SCHEMBL14425217 | 0.73 | RXRA (0.60) | FPR1GNRHRGPR183GPR119RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |