Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | RARG | P13631 | 5/20 | 0.43 |
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | BLVRB | P30043 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 5/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14425219 | 0.83 | FPR1 (0.37) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL14425210 | 0.81 | RARG (0.61) | RARBRARGRARARXRA | |
| SCHEMBL14425212 | 0.80 | RARG (0.47) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL22180634 | 0.80 | RARB (0.53) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL14425245 | 0.79 | RARG (0.58) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL14425239 | 0.78 | CYP26B1 (0.48) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL17049087 | 0.76 | CYP3A4 (0.61) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL26306924 | 0.76 | CYP26A1 (0.47) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL26006715 | 0.76 | RARB (0.50) | TSHRRARBRARGRARACYP26A1 | |
| SCHEMBL24084855 | 0.75 | RARB (0.49) | TSHRRARBRARGRARACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |
| US-7259187-B2 | Tropolone derivatives | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-08-21 | — | — | US | disclosed |