Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292252 | 0.88 | MCHR1 (0.40) | FPR1FPR2MCHR1CYP11B1CYP11B2 | |
| SCHEMBL4288189 | 0.85 | WDR5 (0.41) | FPR1FPR2MCHR1CYP11B1CYP11B2 | |
| SCHEMBL4287520 | 0.84 | FPR1 (0.49) | FPR1FPR2CYP11B1CYP11B2DRD2 | |
| SCHEMBL4287527 | 0.84 | FPR1 (0.49) | FPR1FPR2CYP11B1CYP11B2DRD2 | |
| SCHEMBL13659165 | 0.83 | MCHR1 (0.44) | MCHR1AOC3KCNH2 | |
| SCHEMBL12966613 | 0.79 | AOC3 (0.44) | FPR1FPR2MCHR1CYP11B1CYP11B2 | |
| SCHEMBL13659199 | 0.76 | FPR1 (0.46) | FPR1FPR2AOC3WDR5 | |
| SCHEMBL13659205 | 0.75 | FPR1 (0.46) | FPR1FPR2MCHR1KDRAOC3 | |
| SCHEMBL4290289 | 0.74 | FPR1 (0.47) | FPR1FPR2MCHR1PDGFRBFGFR1 | |
| SCHEMBL4290282 | 0.74 | FPR1 (0.47) | FPR1FPR2MCHR1PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093364-A1 | AZACYCLYL-SUBSTITUTED ARYLDIHYDROISOQUINOLINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |