Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.68 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.58 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.58 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CSF1R | P07333 | 2/20 | 0.58 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465513 | 0.90 | KCNK3 (0.69) | KCNK3KCNK9MAOAMAOBNPC1 | |
| SCHEMBL14426546 | 0.86 | NPC1 (0.73) | KCNK3KCNK9NPC1RAB9ATP53 | |
| SCHEMBL1924651 | 0.84 | KCNK3 (0.66) | KCNK3KCNK9MAOAMAOBNPC1 | |
| SCHEMBL8363018 | 0.83 | SMN1; SMN2 (0.76) | KCNK3KCNK9MAOAMAOBNPC1 | |
| SCHEMBL12192807 | 0.83 | KCNK3 (0.64) | KCNK3KCNK9MAOAMAOBNPC1 | |
| SCHEMBL3675463 | 0.82 | KCNK3 (0.84) | KCNK3KCNK9NPC1RAB9ARXFP1 | |
| SCHEMBL14468045 | 0.82 | MEN1 (0.68) | KCNK3KCNK9RAB9AKCNQ3KCNQ2 | |
| SCHEMBL17620462 | 0.82 | KCNK3 (0.91) | KCNK3KCNK9NPC1RAB9ARXFP1 | |
| SCHEMBL29921751 | 0.82 | KCNK3 (0.63) | KCNK3KCNK9MAOAMAOBNPC1 | |
| SCHEMBL29071358 | 0.82 | KCNK3 (0.63) | KCNK3KCNK9MAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070203184-A1 | Novel Indolin-2-one Derivatives, Their Preparation and the Pharmaceutical Compositions Comprising Them | SANOFI-AVENTIS (FR) | 2007-08-30 | — | — | US | disclosed |
| US-20070203184-A1 | Novel Indolin-2-one Derivatives, Their Preparation and the Pharmaceutical Compositions Comprising Them | SANOFI-AVENTIS (FR) | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203184-A1 | Novel Indolin-2-one Derivatives, Their Preparation and the Pharmaceutical Compositions Comprising Them | OXTR, AVPR2, AVPR1B | KCNK3 809/4885KCNK9 1000/4885MAOA 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.