SCHEMBL14428488

SCHEMBL14428488

COc1cccc(Oc2ccc(C(=O)C(=O)O)c(NC(=O)c3ccccc3)c2)c1

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.66
PYGM P11217 1/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
RAB9A P51151 6/20 0.55
NPC1 O15118 5/20 0.55
NLRP3 Q96P20 1/20 0.55
KCNK9 Q9NPC2 2/20 0.53
KCNK3 O14649 1/20 0.53
PPARG P37231 1/20 0.53
PPARD Q03181 1/20 0.53
GPBAR1 Q8TDU6 1/20 0.53
NR1H4 Q96RI1 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.52
HDAC2 Q92769 1/20 0.52
HTT P42858 1/20 0.51
F10 P00742 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272040 0.90 PGR (0.69) PGRPYGMMEN1KMT2ARAB9A
SCHEMBL2271177 0.84 PYGM (0.72) PGRPYGMMEN1KMT2ARAB9A
SCHEMBL2274026 0.84 PGR (0.61) PGRPYGMMEN1KMT2ARAB9A
SCHEMBL14428494 0.83 PGR (0.66) PGRPYGMMEN1KMT2ARAB9A
SCHEMBL2272706 0.83 MEN1 (0.67) PGRPYGMMEN1KMT2ARAB9A
SCHEMBL2935687 0.82 MEN1 (0.69) PYGMMEN1KMT2ARAB9ANPC1
SCHEMBL2271007 0.81 MEN1 (0.69) PGRPYGMMEN1KMT2AKCNK9
SCHEMBL15233666 0.81 MEN1 (0.63) PGRMEN1KMT2ARAB9ANPC1
SCHEMBL2269238 0.81 KDM4E (0.68) MEN1KMT2ARAB9ANPC1NLRP3
SCHEMBL2293458 0.80 PGR (0.67) PGRPYGMMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed