Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 4/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380778 | 0.93 | MAPK1 (0.37) | MAPK1HSP90AA1HSP90AB1AKT1BRPF1 | |
| SCHEMBL14428802 | 0.93 | AKT1 (0.44) | MAPK1AKT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14428800 | 0.91 | MAPT (0.42) | MAPK1HSP90AA1HSP90AB1AKT1ALDH1A1 | |
| SCHEMBL14440557 | 0.85 | MAPT (0.38) | MAPK1HSP90AA1HSP90AB1AKT1ALDH1A1 | |
| SCHEMBL5400741 | 0.85 | AKT1 (0.44) | MAPK1AKT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5396837 | 0.83 | CA1 (0.43) | MAPK1HSP90AA1HSP90AB1AKT1ALDH1A1 | |
| SCHEMBL14428801 | 0.83 | CA1 (0.43) | MAPK1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5400308 | 0.83 | DEGS1 (0.40) | HSP90AA1HDAC3HDAC1POLBNPSR1 | |
| SCHEMBL5392619 | 0.82 | BRPF1 (0.46) | BRPF1ALDH1A1POLBNPSR1SMN1; SMN2 | |
| SCHEMBL14504496 | 0.81 | BRPF1 (0.45) | MAPK1HSP90AA1HSP90AB1BRPF1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | DDC, DPP3, AMPD3 | MAPK1 3725/4885HSP90AA1 1591/4885HSP90AB1 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.