Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5852058 | 0.88 | CA1 (0.41) | KMT2AHTTCYP2C9CYP2C19MAPT | |
| SCHEMBL21283006 | 0.84 | MAPT (0.46) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5981947 | 0.83 | KMT2A (0.45) | KMT2AHTTCYP2C19MAPTCA1 | |
| SCHEMBL18868657 | 0.82 | MAPT (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5981210 | 0.81 | HTT (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3751041 | 0.80 | CA1 (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1561831 | 0.80 | CA1 (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1263178 | 0.80 | CA1 (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2562479 | 0.80 | CA1 (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19970649 | 0.80 | CA1 (0.45) | KMT2AHTTCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | IDENIX PHARMACEUTICALS, INC. | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185063-A1 | Seven-membered ring nucleosides | NSUN2, NSUN3, HAVCR2 | KMT2A 3044/4885HTT 3228/4885CTSL 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.