Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429286 | 0.88 | KMT2A (0.43) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5981947 | 0.84 | KMT2A (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL2562479 | 0.84 | CA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL1263178 | 0.84 | CA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL1561831 | 0.84 | CA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL3751041 | 0.84 | CA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL19970649 | 0.84 | CA1 (0.45) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL3631853 | 0.83 | HTT (0.43) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5981793 | 0.82 | HTT (0.43) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL5981210 | 0.82 | HTT (0.45) | CA1CA2CA7CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135578-B2 | Antiarthritic agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-11-14 | — | — | US | disclosed |
| EP-1181274-A4 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | SCRIPPS RESEARCH INST (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20040198772-A1 | Iminocyclitol inhibitors of hexoaminidase and glycosidase | THE SCRIPPS RESEARCH INSTITUTE | 2004-10-07 | — | — | US | disclosed |
| US-6774140-B1 | ANTIARTHRITIC AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2004-08-10 | — | — | US | disclosed |
| EP-1181274-A1 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | The Scripps Research Institute (US) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000068194-A1 | IMINOCYCLITOL INHIBITORS OF HEXOAMINIDASE AND GLYCOSIDASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198772-A1 | Iminocyclitol inhibitors of hexoaminidase and glycosidase | ENGASE, HEXD, MGAM | CA1 766/4885CA2 847/4885CA7 628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.