Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21283006 | 0.91 | MAPT (0.46) | MAPTHTTKMT2ARCE1CA1 | |
| SCHEMBL14429286 | 0.82 | KMT2A (0.43) | MAPTHTTKMT2ARCE1CA1 | |
| SCHEMBL16429136 | 0.81 | CA1 (0.43) | HTTKMT2ACA1CA2CA7 | |
| SCHEMBL9837867 | 0.81 | CA1 (0.43) | HTTKMT2ACA1CA2CA7 | |
| SCHEMBL14429284 | 0.78 | KMT2A (0.43) | HTTKMT2ACA1CA2CA7 | |
| SCHEMBL12636372 | 0.78 | KMT2A (0.50) | MAPTHTTKMT2ACA1CA2 | |
| SCHEMBL26759878 | 0.78 | MAPT (0.43) | MAPTKMT2ARCE1CYP3A4CYP2C9 | |
| SCHEMBL23867737 | 0.77 | MAPT (0.43) | MAPTKMT2ARCE1CYP2C9CYP2C19 | |
| SCHEMBL21283007 | 0.76 | KMT2A (0.42) | HTTKMT2ACA1CA2CA7 | |
| SCHEMBL6101469 | 0.75 | CA1 (0.47) | MAPTHTTKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083830-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING INKT CELLS | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2017-05-18 | — | — | WO | disclosed |