Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713860 | 0.79 | KDM1A (0.42) | KDM1ADEGS1GAAESRRGTDP1 | |
| SCHEMBL9814341 | 0.77 | KDM1A (0.41) | KDM1ADEGS1GAAESRRGTDP1 | |
| SCHEMBL7551195 | 0.77 | KDM1A (0.41) | KDM1ADEGS1GAAESRRGTDP1 | |
| SCHEMBL28792582 | 0.77 | KDM1A (0.41) | KDM1ADEGS1GAAESRRGTDP1 | |
| SCHEMBL3442788 | 0.73 | KDM1A (0.39) | KDM1ADEGS1ESRRGALDH1A1MAPK1 | |
| SCHEMBL3442786 | 0.73 | KDM1A (0.39) | KDM1ADEGS1ESRRGALDH1A1MAPK1 | |
| SCHEMBL10604768 | 0.72 | CES1 (0.41) | KDM1ADEGS1TDP1ALDH1A1MAPK1 | |
| SCHEMBL17616707 | 0.72 | CES1 (0.41) | KDM1ADEGS1TDP1ALDH1A1MAPK1 | |
| SCHEMBL2989490 | 0.72 | KDM1A (0.38) | KDM1ADEGS1ESRRGALDH1A1MAPK1 | |
| SCHEMBL4252800 | 0.71 | KDM1A (0.37) | KDM1ADEGS1ESRRGALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1816136-A1 | GPR7-SELECTIVE LIGAND AND USE THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |