Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196153 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AKDM4EGAARARA | |
| SCHEMBL5194112 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AKDM4EGAARARA | |
| SCHEMBL5196876 | 0.77 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKDM4ERARARARB | |
| SCHEMBL5193911 | 0.74 | RAB9A (0.42) | SMN1; SMN2RAB9AKDM4EGAAMAPT | |
| SCHEMBL5193285 | 0.72 | POLB (0.51) | SMN1; SMN2RAB9AKDM4EGAAMAPT | |
| SCHEMBL5196161 | 0.71 | RAB9A (0.46) | SMN1; SMN2RAB9AKDM4EGAARARA | |
| SCHEMBL1327631 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AKDM4EGAAMAPT | |
| SCHEMBL5196998 | 0.69 | CYP1A2 (0.48) | SMN1; SMN2RAB9AKDM4EMAPTL3MBTL1 | |
| SCHEMBL8868807 | 0.69 | RAB9A (0.85) | SMN1; SMN2RAB9AKDM4EGAAMAPT | |
| SCHEMBL892234 | 0.69 | RAB9A (1.00) | SMN1; SMN2RAB9AKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | disclosed |