Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5196165 | 0.89 | MAPT (0.45) | RAB9ANPC1LMNAKMT2APOLB | |
| SCHEMBL5194116 | 0.85 | USP2 (0.40) | RAB9ANPC1LMNAKMT2ATRPM8 | |
| SCHEMBL5196153 | 0.83 | SMN1; SMN2 (0.55) | RAB9ANPC1LMNAKMT2APOLB | |
| SCHEMBL5197734 | 0.80 | POLB (0.49) | RAB9ANPC1KMT2APOLBTRPM8 | |
| SCHEMBL5193911 | 0.79 | RAB9A (0.42) | RAB9ANPC1LMNAKMT2APOLB | |
| SCHEMBL5195687 | 0.77 | CYP1A2 (0.47) | RAB9ANPC1KMT2APOLBTRPM8 | |
| SCHEMBL3816560 | 0.75 | HSD17B1 (0.44) | RAB9ANPC1LMNAKMT2APOLB | |
| SCHEMBL13685249 | 0.73 | SMN1; SMN2 (0.61) | RAB9ANPC1LMNAKMT2ATRPM8 | |
| SCHEMBL5196876 | 0.72 | SMN1; SMN2 (0.53) | RAB9ANPC1LMNAKMT2APOLB | |
| SCHEMBL14430682 | 0.71 | SMN1; SMN2 (0.52) | RAB9ANPC1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321463-B1 | Thiazole derivatives and their use for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC (CA) | 2007-08-08 | — | — | EP | claimed |