SCHEMBL1443076

SCHEMBL1443076

c1ccc(C2CCOCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 3/20 0.54
SIGMAR1 Q99720 1/20 0.54
GRIN2B Q13224 3/20 0.42
DRD2 P14416 1/20 0.42
TSHR P16473 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
KDM1A O60341 1/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL16296636 0.98 SLC18A3 (0.52) SLC18A3SIGMAR1GRIN2BDRD2TSHR
SCHEMBL19094052 0.91 SLC18A3 (0.47) SLC18A3SIGMAR1TSHRGAAMAPT
SCHEMBL19539969 0.89 SLC18A3 (0.46) SLC18A3SIGMAR1TSHRGAAMAPT
SCHEMBL7943971 0.87 NPC1 (0.55) SLC18A3SIGMAR1GAAKDM1AMAOB
SCHEMBL23050200 0.86 SLC18A3 (0.45) SLC18A3SIGMAR1GRIN2BTSHRGAA
SCHEMBL2479517 0.86 SLC18A3 (0.45) SLC18A3SIGMAR1GRIN2BTSHRGAA
SCHEMBL190417 0.81 SLC18A3 (0.67) SLC18A3SIGMAR1GRIN2BDRD2GAA
SCHEMBL41763 0.81
SCHEMBL4483396 0.80 SLC18A3 (0.69) SLC18A3SIGMAR1GRIN2BTSHRKDM1A
SCHEMBL20499599 0.79 HPGD (0.53) TSHRGAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118136967-B Lithium metal battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-08-06 CN claimed
CN-118136967-A Lithium metal battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-06-04 CN claimed
EP-4165033-A1 SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF Betta Pharmaceuticals Co., Ltd (CN) 2023-04-19 EP claimed
WO-2021249449-A1 SHP2 INHIBITORS, COMPOSITIONS AND USES THEREOF BETTA PHARMACEUTICALS CO., LTD (CN) 2021-12-16 WO claimed
WO-2020210428-A1 NOVEL INHIBITORS OF FLAVIVIRUS PROTEASE FOR PREVENTION AND TREATMENT OF ZIKA, DENGUE AND OTHER FLAVIVIRUS INFECTIONS BAYLOR COLLEGE OF MEDICINE (US) 2020-10-15 WO claimed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
CN-118136967-B Lithium metal battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-08-06 CN disclosed
CN-118136967-A Lithium metal battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-06-04 CN disclosed
CN-117813154-A Polyamide-based microcapsules 弗门尼舍有限公司 2024-04-02 CN disclosed
WO-2023117914-A1 CYCLOPENTATHIOPHENE CARBOXAMIDE DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-06-29 WO disclosed
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed
EP-1465008-B1 Silver halide photographic light-sensitive material FUJIFILM CORP (JP) 2008-07-16 EP disclosed
US-20070197624-A1 Acylated amino acid amidyl pyrazoles and related compounds ELAN PHARMACEUTICALS, INC. (US) 2007-08-23 US disclosed
EP-1633350-A2 ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS Elan Pharmaceuticals, Inc. (US) 2006-03-15 EP disclosed
WO-2005009344-A2 ACYLATED AMINO ACID AMIDYL PYRAZOLES AND RELATED COMPOUNDS ELAN PHARMACEUTICALS, INC. (US) 2005-02-03 WO disclosed
EP-0294220-B1 Photopolymerizable composition HITACHI CHEMICAL CO LTD (JP) 1994-05-25 EP disclosed
US-5034429-A An unsaturated monomer, a photoinitiator and a benzene derivative for providing a cured film HITACHI CHEMICAL CO., LTD. (JP) 1991-07-23 US disclosed
EP-0294220-A2 Photopolymerizable composition Hitachi Chemical Co., Ltd. (JP) 1988-12-07 EP disclosed
US-4078076-A HYPOLIPEMIC ACTIVITY ROUSSEL UCLAF (FR) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 SLC18A3 3295/4885SIGMAR1 4838/4885GRIN2B 1845/4885
US-20070197624-A1 Acylated amino acid amidyl pyrazoles and related compounds APP, BACE1, APH1A SLC18A3 414/4885SIGMAR1 4323/4885GRIN2B 461/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 SLC18A3 4567/4885SIGMAR1 3591/4885GRIN2B 4630/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 SLC18A3 4567/4885SIGMAR1 3591/4885GRIN2B 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.