SCHEMBL14432137

SCHEMBL14432137

Cc1cc(Cl)c(C2=C(O)COC2=O)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPIA P62937 1/20 0.38
MAOA P21397 1/20 0.38
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28806288 0.73 MAOA (0.41) MAOA
SCHEMBL26767267 0.72 PPIA (0.43) PPIAMAOAKDM4EALDH1A1GAA
SCHEMBL28066481 0.70 NUAK1 (0.36) KDM4EGAASMN1; SMN2
SCHEMBL24822260 0.68 CYP3A4 (0.51) PPIAMAOAKDM4EALDH1A1GAA
SCHEMBL26767243 0.68 PPIA (0.45) PPIAMAOAKDM4EALDH1A1GAA
SCHEMBL12107994 0.66 AHR (0.56) MAOAKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL14432147 0.65 ACACB (0.37) KDM4EALDH1A1GAASMN1; SMN2
SCHEMBL14432179 0.65 GRIN2D (0.34) MAOAKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL11350152 0.64 GRIN2D (0.42) MAOAKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL2645065 0.64 PTGS1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed