SCHEMBL14432179

SCHEMBL14432179

Cc1cc(Cl)c(C2=C(O)C(C)NC2=O)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
MAOA P21397 1/20 0.34
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14432182 0.75 NPC1 (0.31) ALDH1A1
SCHEMBL14432147 0.73 ACACB (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13673438 0.69 STK10 (0.38) GAALMNA
SCHEMBL12269978 0.68 STK10 (0.36) KDM4EGAA
SCHEMBL12107994 0.65 AHR (0.56) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL14432137 0.65 PPIA (0.38) MAOAKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL11057362 0.63 PPOX (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL23727834 0.63 MKNK2 (0.38) KDM4EALDH1A1GAASMN1; SMN2LMNA
SCHEMBL23745465 0.63 MKNK2 (0.38) KDM4EALDH1A1GAASMN1; SMN2LMNA
SCHEMBL120848 0.60 CD44 (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed
US-7256158-B2 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides BAYER AG (DE) 2007-08-14 US disclosed