Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454855 | 0.89 | FAAH (0.54) | FAAHCYP4F2CYP4A11LMNAMAPT | |
| SCHEMBL2463086 | 0.83 | FAAH (0.52) | FAAHCYP4F2CYP4A11HDAC1 | |
| SCHEMBL12064714 | 0.79 | GPR119 (0.59) | FAAHGPR119 | |
| SCHEMBL2458531 | 0.78 | FAAH (0.58) | FAAHLMNAMAPTMEN1KMT2A | |
| SCHEMBL2463633 | 0.75 | FAAH (0.69) | FAAHLMNAMEN1KMT2AGPR119 | |
| SCHEMBL13246348 | 0.75 | GRIN2B (0.60) | LMNAMAPTMEN1KMT2AGRIN2B | |
| SCHEMBL2456940 | 0.73 | HRH2 (0.51) | LMNAMAPTMEN1KMT2AGRIN2B | |
| SCHEMBL14627810 | 0.72 | FAAH (0.79) | FAAHLMNA | |
| SCHEMBL2457230 | 0.72 | FAAH (0.51) | FAAHLMNAMEN1KMT2AGPR119 | |
| SCHEMBL5448245 | 0.71 | FAAH (0.58) | FAAHLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708994-B1 | ARYLOXYALKYLCARBAMATE-TYPE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2007-08-08 | — | — | EP | disclosed |