Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432791 | 0.91 | MEN1 (0.40) | CYP1A2ALDH1A1LMNACCR5KMT2A | |
| SCHEMBL5229698 | 0.86 | TP53 (0.42) | CYP1A2CCR5CHEK1TP53 | |
| SCHEMBL14432488 | 0.84 | NAMPT (0.40) | CYP1A2ALDH1A1MAPTCCR5KMT2A | |
| SCHEMBL14432776 | 0.83 | TP53 (0.47) | CYP1A2ALDH1A1LMNAPOLBCCR5 | |
| SCHEMBL14432801 | 0.83 | CYP1A2 (0.41) | CYP1A2LMNAMAPTCCR5KMT2A | |
| SCHEMBL14432873 | 0.82 | PPARG (0.41) | CYP1A2ALDH1A1LMNAPOLBCCR5 | |
| SCHEMBL14432821 | 0.82 | HDAC1 (0.44) | ALDH1A1LMNAGAAMAPTKMT2A | |
| SCHEMBL5228484 | 0.81 | TP53 (0.44) | ALDH1A1LMNAGAAPOLBMAPT | |
| SCHEMBL14433142 | 0.81 | ALDH1A1 (0.47) | CYP1A2ALDH1A1LMNAPOLBCCR5 | |
| SCHEMBL14432787 | 0.80 | PPARG (0.48) | CYP1A2POLBCCR5IRAK4CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581528-B1 | PIPERIDINYL-THIAZOLE CARBOXYLIC ACID DERIVATIVES AS ANGIOGENESIS INHIBITORS | METRIS THERAPEUTICS LTD (GB) | 2007-08-01 | — | — | EP | disclosed |