Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432776 | 0.88 | TP53 (0.47) | ALDH1A1L3MBTL1TP53UBE2MDCUN1D1 | |
| SCHEMBL14432801 | 0.85 | CYP1A2 (0.41) | L3MBTL1TP53LMNACYP1A2STAT3 | |
| SCHEMBL13422402 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TP53UBE2MDCUN1D1 | |
| SCHEMBL5229557 | 0.83 | HPGD (0.46) | ALDH1A1L3MBTL1TP53LMNACYP1A2 | |
| SCHEMBL6233245 | 0.83 | SPR (0.40) | ALDH1A1L3MBTL1TP53LMNACYP1A2 | |
| SCHEMBL14432861 | 0.81 | TP53 (0.43) | ALDH1A1L3MBTL1TP53UBE2MDCUN1D1 | |
| SCHEMBL14432873 | 0.81 | PPARG (0.41) | ALDH1A1L3MBTL1TP53LMNACYP1A2 | |
| SCHEMBL14432488 | 0.81 | NAMPT (0.40) | ALDH1A1L3MBTL1CYP1A2STAT3PIM1 | |
| SCHEMBL13422133 | 0.81 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TP53UBE2MDCUN1D1 | |
| SCHEMBL14432804 | 0.81 | CYP1A2 (0.43) | ALDH1A1TP53LMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581528-B1 | PIPERIDINYL-THIAZOLE CARBOXYLIC ACID DERIVATIVES AS ANGIOGENESIS INHIBITORS | METRIS THERAPEUTICS LTD (GB) | 2007-08-01 | — | — | EP | disclosed |