SCHEMBL29400770

SCHEMBL29400770

CSC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 3/20 0.58
TP53 P04637 3/20 0.58
CASP3 P42574 2/20 0.55
SLC17A5 Q9NRA2 1/20 0.55
TLR2 O60603 2/20 0.52
MDM2 Q00987 5/20 0.52
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3436129 1.00 MDM4 (0.58) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL1001473 1.00 MDM4 (0.58) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL19661184 0.92 TLR2 (0.58) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL9288118 0.91 KMT2A (0.51) MDM4TP53CASP3SLC17A5MDM2
SCHEMBL14432835 0.91 MDM4 (0.59) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL14788958 0.91 MDM4 (0.59) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL800305 0.89 FDFT1 (0.57) MDM4TP53CASP3TLR2MDM2
SCHEMBL1486194 0.89 SLC17A5 (0.58) MDM4TP53CASP3SLC17A5TLR2
SCHEMBL4600701 0.89 FDFT1 (0.57) MDM4TP53CASP3TLR2MDM2
SCHEMBL800035 0.89 FDFT1 (0.57) MDM4TP53CASP3TLR2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039383-A Preparation method of leuprorelin impurity K 深圳市健元医药科技有限公司 2024-11-29 CN claimed
CN-115819511-A Preparation method and application of giant salamander hydrolyzed collagen active peptide 广州远想医学生物技术有限公司 2023-03-21 CN claimed
CN-119039383-A Preparation method of leuprorelin impurity K 深圳市健元医药科技有限公司 2024-11-29 CN disclosed
CN-118772247-A PKal bicyclic peptide and application thereof in medicine 西藏海思科制药有限公司 2024-10-15 CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2024-01-11 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
US-20230157302-A1 METHODS FOR INHIBITING FUSARIUM MYCOTOXIN PRODUCTION INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (FR) 2023-05-25 US disclosed
CN-116063461-A Skin repair peptide and application thereof 广州远想医学生物技术有限公司 2023-05-05 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
CN-115819511-A Preparation method and application of giant salamander hydrolyzed collagen active peptide 广州远想医学生物技术有限公司 2023-03-21 CN disclosed
EP-4139336-A1 METHODS FOR INHIBITING FUSARIUM MYCOTOXIN PRODUCTION Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (FR) 2023-03-01 EP disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
EP-4011904-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-06-15 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SPINT2, SERPINB1 MDM4 3411/4885TP53 2928/4885CASP3 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.