Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892403 | 0.74 | KDM4E (0.63) | KDM4ELMNATHRBPOLBAPEX1 | |
| SCHEMBL22103882 | 0.73 | KDM4E (0.42) | KDM4ELMNATHRBPOLBAPEX1 | |
| SCHEMBL510221 | 0.67 | — | — | |
| Maleic Anhydride SCHEMBL6318875 | 0.67 | KDM4E (0.46) | KDM4ELMNATHRBPOLBAPEX1 | |
| SCHEMBL14845642 | 0.66 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL8764997 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL476049 | 0.65 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL24004713 | 0.65 | KDM4E (0.61) | KDM4ELMNATHRBPOLBAPEX1 | |
| SCHEMBL75505 | 0.65 | KDM4E (0.61) | KDM4ELMNATHRBPOLBAPEX1 | |
| SCHEMBL21705290 | 0.65 | KDM4E (0.61) | KDM4ELMNATHRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262299-B2 | Diels-Alder reaction; using zeolite y in exchanged with copper; separated from mixture for reuse | JOHNSON MATTHEY PLC (GB) | 2007-08-28 | — | — | US | disclosed |
| US-7262299-B2 | Diels-Alder reaction; using zeolite y in exchanged with copper; separated from mixture for reuse | JOHNSON MATTHEY PLC (GB) | 2007-08-28 | — | — | US | disclosed |