SCHEMBL8764997

SCHEMBL8764997

O=C1C[C@H](C(=O)O)C(=O)O1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CTRC Q99895 1/20 0.32
CTRB1 P17538 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476049 1.00 ALDH1A1 (0.32) ALDH1A1CTRCCTRB1
SCHEMBL625136 0.79 SMN1; SMN2 (0.32) ALDH1A1
SCHEMBL510221 0.79
SCHEMBL575023 0.79 SMN1; SMN2 (0.32) ALDH1A1
SCHEMBL10965455 0.76 SMN1; SMN2 (0.30)
SCHEMBL510112 0.74
SCHEMBL8990080 0.74
SCHEMBL9321649 0.74
SCHEMBL15974800 0.74
SCHEMBL29049316 0.73 SMN1; SMN2 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0528044-B1 Process for producing 4-substituted gamma- lactone, and the so produced novel substances. JAPAN TOBACCO INC (JP) 1997-08-13 EP disclosed
US-5374744-A Sex pheronome of Japanese beetle, cupreous chafers; oxidation, reduction, cleavage, cyclization, alkynylation, hydrolysis JAPAN TOBACCO INC. (JP) 1994-12-20 US disclosed
EP-0528044-A1 PROCESS FOR PRODUCING 4-SUBSTITUTED $g(g)-LACTONE, AND NOVEL SUBSTANCE JAPAN TOBACCO INC. (JP) 1993-02-24 EP disclosed