Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 7/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840666 | 0.85 | LMNA (0.63) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4555003 | 0.83 | IDO1 (0.78) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7592691 | 0.79 | ALDH1A1 (0.62) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL28145455 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6815899 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL5038742 | 0.78 | ALDH1A1 (0.56) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7592685 | 0.77 | ALDH1A1 (0.60) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6813529 | 0.77 | P2RY1 (0.61) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL10660750 | 0.76 | IDO1 (0.68) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4555049 | 0.76 | MEN1 (0.68) | MAPTALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076055-A9 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED INC (US) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007076055-A2 | COMPOSITIONS AND METHODS COMPRISING PROTEINASE ACTIVATED RECEPTOR ANTAGONISTS | ENTREMED, INC. (US) | 2007-07-05 | — | — | WO | disclosed |