Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434670 | 0.93 | F10 (0.39) | F10KMT2AMETALKNPC1 | |
| SCHEMBL12371499 | 0.92 | F10 (0.39) | F10KMT2AMETALKNPC1 | |
| SCHEMBL14434665 | 0.90 | F10 (0.41) | F10KMT2AMETALKNPC1 | |
| SCHEMBL12371500 | 0.85 | F10 (0.39) | F10KMT2AMETALKNPC1 | |
| SCHEMBL14434669 | 0.84 | F10 (0.41) | F10KMT2ANPC1POLBTSHR | |
| SCHEMBL12371435 | 0.82 | F10 (0.49) | F10KMT2AMETALKPOLB | |
| SCHEMBL12371503 | 0.82 | F10 (0.41) | F10KMT2AMETALKNPC1 | |
| SCHEMBL12371434 | 0.82 | F10 (0.49) | F10KMT2AMETALKPOLB | |
| SCHEMBL12101413 | 0.79 | F10 (0.43) | F10NPC1TSHRKLKB1CFD | |
| SCHEMBL14434249 | 0.77 | F10 (0.41) | F10KMT2ANPC1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093595-A1 | SUBSTITUTED PROLINAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-08-23 | — | — | WO | disclosed |