Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14434468 | 0.92 | POLB (0.56) | POLBMAPK1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5318873 | 0.92 | POLB (0.58) | POLBMAPK1SMN1; SMN2MCL1MEN1 | |
| SCHEMBL14434470 | 0.91 | POLB (0.55) | POLBMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14434878 | 0.91 | POLB (0.57) | POLBMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5375793 | 0.89 | POLB (0.53) | POLBMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5435703 | 0.89 | ALDH1A1 (0.53) | POLBMAPTSMN1; SMN2MCL1ALDH1A1 | |
| SCHEMBL14434885 | 0.89 | POLB (0.52) | POLBMAPK1MEN1KMT2ALMNA | |
| SCHEMBL14434465 | 0.87 | POLB (0.53) | POLBMAPK1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL14434880 | 0.87 | POLB (0.53) | POLBMEN1KMT2ALMNAHTT | |
| SCHEMBL5501882 | 0.86 | POLB (0.70) | POLBMAPK1MAPTSMN1; SMN2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |