Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13993792 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1POLB | |
| SCHEMBL14446811 | 0.83 | TSHR (0.35) | KDM4EALDH1A1POLBTSHRPDE5A | |
| SCHEMBL22014309 | 0.79 | TSHR (0.50) | KDM4EALDH1A1POLBTSHR | |
| SCHEMBL57456 | 0.75 | ALDH1A1 (0.43) | ALDH1A1POLB | |
| SCHEMBL14435105 | 0.73 | ALDH1A1 (0.39) | KDM4EALDH1A1POLBTSHR | |
| Water SCHEMBL23355919 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLB | |
| Water SCHEMBL9364486 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLB | |
| SCHEMBL13631583 | 0.72 | TSHR (0.43) | KDM4EALDH1A1POLBTSHR | |
| SCHEMBL1305572 | 0.71 | TSHR (0.46) | KDM4EALDH1A1POLBTSHR | |
| SCHEMBL647080 | 0.70 | ALDH1A1 (0.44) | KDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | JIN HAOLUN | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185007-A1 | Aza-quinolinol phosphonate integrase inhibitor compounds | CDKL5, CDKL1, CDKL3 | KDM4E 303/4885ALDH1A1 2811/4885POLB 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.