Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346565 | 0.88 | PTGS2 (0.54) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL13681337 | 0.88 | PTGS2 (0.54) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL30578089 | 0.79 | PTGS2 (0.65) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL29055589 | 0.79 | PTGS2 (0.65) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL8922667 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL2677602 | 0.79 | PTGS2 (0.48) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| Ammonia Solution, Strong SCHEMBL28229773 | 0.78 | PTGS2 (0.62) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL2678000 | 0.77 | PTGS1 (0.56) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL8924011 | 0.77 | PTGS1 (0.56) | PTGS2PTGS1MAPTALDH1A1CXCR1 | |
| SCHEMBL2678004 | 0.77 | PTGS1 (0.56) | PTGS2PTGS1MAPTALDH1A1CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089745-A2 | NOVEL COMPOUNDS WITH HIGH THERAPEUTIC INDEX | SIGNATURE R & D HOLDINGS, LLC (US) | 2007-08-09 | — | — | WO | disclosed |