SCHEMBL14435190

SCHEMBL14435190

C=C(c1cc(OC)ccc1CC)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
POLB P06746 1/20 0.43
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
KDM2B Q8NHM5 6/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
CHRM2 P08172 3/20 0.40
CHRM4 P08173 3/20 0.40
CHRM1 P11229 3/20 0.40
CHRM3 P20309 3/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941437 0.76 CYP3A4 (0.43) POLBKDM4EALDH1A1HPGDHSD17B10
SCHEMBL16951695 0.72 CYP3A4 (0.46) POLBKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12328328 0.71 KDM4E (0.50) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL14466515 0.71 ALDH1A1 (0.58) KMT2APOLBKDM4EALDH1A1HPGD
SCHEMBL13469239 0.71 SMN1; SMN2 (0.57) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL14467211 0.70 ABCG2 (0.44) POLBALDH1A1HPGDHSD17B10MAPK1
SCHEMBL4115692 0.70 KDM2B (0.47) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL4113759 0.70 MAPT (0.61) KDM4EALDH1A1HPGDKDM2BPTGDR2
SCHEMBL16238926 0.69 POLB (0.45) MEN1KMT2APOLBKDM4EALDH1A1
SCHEMBL13469244 0.69 KDM4E (0.58) MEN1KMT2APOLBKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007090434-A1 SUBSTITUTED ARYL OXIMES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-08-16 WO disclosed