Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513116 | 1.00 | KMT2A (0.42) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL14435196 | 1.00 | KMT2A (0.42) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL22724865 | 0.98 | KMT2A (0.41) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL17237661 | 0.98 | KMT2A (0.41) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL30920971 | 0.95 | — | — | |
| SCHEMBL17525362 | 0.82 | CYP3A4 (0.33) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL13559798 | 0.81 | HTR2A (0.40) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL27872501 | 0.81 | SIGMAR1 (0.34) | KMT2ALMNAPOLBCYP2D6ALDH1A1 | |
| SCHEMBL18871964 | 0.79 | KMT2A (0.46) | KMT2ADRD2HTR2AHRH1LMNA | |
| SCHEMBL13505803 | 0.79 | SMN1; SMN2 (0.37) | KMT2ADRD2HTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096186-A1 | SUBSTITUTED PHENYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2007-08-30 | — | — | WO | disclosed |