⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435195 | 0.95 | KMT2A (0.42) | — | |
| SCHEMBL6513116 | 0.95 | KMT2A (0.42) | — | |
| SCHEMBL14435196 | 0.95 | KMT2A (0.42) | — | |
| SCHEMBL17237661 | 0.93 | KMT2A (0.41) | — | |
| SCHEMBL22724865 | 0.93 | KMT2A (0.41) | — | |
| SCHEMBL13559798 | 0.81 | HTR2A (0.40) | — | |
| SCHEMBL27872501 | 0.81 | SIGMAR1 (0.34) | — | |
| SCHEMBL13505803 | 0.79 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL18871964 | 0.79 | KMT2A (0.46) | — | |
| SCHEMBL20259872 | 0.78 | SIGMAR1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637461-B2 | Compounds for the activation of AMPK | PFIZER INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20240182468-A1 | COMPOUNDS FOR THE ACTIVATION OF AMPK | PFIZER (US) | 2024-06-06 | — | — | US | disclosed |