Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874916 | 0.90 | PRKCA (0.50) | PRKCAMMP12NR1I2SCN9ACCNB2 | |
| SCHEMBL925855 | 0.87 | CDK1 (0.46) | PRKCAMMP12NR1I2SCN9ACCNB2 | |
| SCHEMBL14263673 | 0.86 | SCN9A (0.38) | PRKCAMMP12SCN9AGSK3BCDK5 | |
| SCHEMBL14435944 | 0.85 | SCN9A (0.43) | PRKCAMMP12NR1I2SCN9A | |
| SCHEMBL991506 | 0.84 | PRKCA (0.39) | PRKCAMMP12NR1I2SCN9ACCNB2 | |
| SCHEMBL14253194 | 0.83 | SCN9A (0.62) | NR1I2SCN9A | |
| SCHEMBL792582 | 0.83 | CCNB2 (0.39) | PRKCAMMP12NR1I2CCNB2CDK1 | |
| SCHEMBL5256403 | 0.82 | OPRM1 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL14253262 | 0.82 | NR1I2 (0.62) | PRKCAMMP12NR1I2SCN9A | |
| SCHEMBL14253314 | 0.82 | CYP3A4 (0.41) | PRKCAMMP12NR1I2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |