Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821597 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CCR3KDM4EL3MBTL1S1PR3 | |
| SCHEMBL14263679 | 0.86 | SCN9A (0.36) | CCR3HDAC1HDAC8HDAC6 | |
| SCHEMBL10293471 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1TSHRMAPK1 | |
| SCHEMBL5300454 | 0.80 | PRKCA (0.40) | ALDH1A1KDM4EL3MBTL1HSD17B10NPSR1 | |
| SCHEMBL772713 | 0.79 | CNR2 (0.42) | ALDH1A1CCR3KDM4EL3MBTL1MAPK1 | |
| SCHEMBL14263698 | 0.78 | SCN9A (0.36) | HSD17B10MAPTGAACNR2HDAC1 | |
| SCHEMBL13286194 | 0.77 | MEN1 (0.36) | ALDH1A1L3MBTL1MEN1KMT2AHDAC1 | |
| SCHEMBL792427 | 0.77 | CNR2 (0.41) | ALDH1A1CCR3KDM4EL3MBTL1RAB9A | |
| SCHEMBL391724 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EL3MBTL1RAB9ATSHR | |
| SCHEMBL3098417 | 0.76 | ALDH1A1 (0.37) | ALDH1A1KDM4EALOX15HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |