Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31631868 | 0.87 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL24102662 | 0.86 | DGAT1 (0.38) | DGAT1BRD4CREBBPPDE10A | |
| SCHEMBL31631877 | 0.86 | DGAT1 (0.38) | DGAT1BRD4CREBBPPDE10A | |
| SCHEMBL2082136 | 0.86 | DGAT1 (0.38) | DGAT1BRD4CREBBPPDE10A | |
| SCHEMBL12118691 | 0.83 | DGAT1 (0.44) | DGAT1BRD4CREBBP | |
| SCHEMBL13722210 | 0.82 | DGAT1 (0.40) | DGAT1BRD4CREBBPPDE10A | |
| SCHEMBL31629427 | 0.80 | DGAT1 (0.38) | DGAT1BRD4CREBBP | |
| SCHEMBL17675396 | 0.79 | DGAT1 (0.39) | DGAT1BRD4CREBBP | |
| SCHEMBL2822527 | 0.79 | DUT (0.39) | DGAT1 | |
| SCHEMBL27284918 | 0.79 | F2RL1 (0.34) | DGAT1BRD4CREBBPF2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |