Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435381 | 0.90 | SMN1; SMN2 (0.38) | KCNA5PTGER2SMN1; SMN2SLC6A3 | |
| SCHEMBL4456765 | 0.83 | POLB (0.42) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL4469178 | 0.83 | POLB (0.41) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL14435380 | 0.82 | ROCK2 (0.36) | KCNA5POLBL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13971462 | 0.81 | KCNA5 (0.38) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL4458292 | 0.81 | POLB (0.42) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL4457249 | 0.81 | KCNA5 (0.61) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL4470641 | 0.79 | POLB (0.37) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL4458360 | 0.79 | POLB (0.37) | KCNA5KCNE1KCNQ1KCND3POLB | |
| SCHEMBL13971459 | 0.78 | CYP2C9 (0.39) | KCNA5KCNE1KCNQ1KCND3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007089679-A2 | POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2007-08-09 | — | — | WO | disclosed |