Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822208 | 0.87 | HDAC1 (0.41) | SCN9ATLR7TLR8CYP3A4CYP2C19 | |
| SCHEMBL14263519 | 0.83 | ACP1 (0.33) | TLR7CNR2ACP1 | |
| SCHEMBL4826344 | 0.80 | SCN9A (0.41) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL14263637 | 0.78 | PARP1 (0.41) | ACP1 | |
| SCHEMBL14607007 | 0.76 | HDAC1 (0.41) | SCN9ACNR2HDAC1HDAC8HDAC6 | |
| SCHEMBL4829898 | 0.75 | SCN9A (0.38) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL27693444 | 0.75 | CNR2 (0.38) | CNR2HDAC1HDAC8HDAC6CNR1 | |
| SCHEMBL3721352 | 0.74 | PDE4D (0.35) | SCN9ACYP3A4CYP2C19CYP2C9HDAC1 | |
| SCHEMBL3091875 | 0.73 | PRKCA (0.40) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL3571468 | 0.73 | FABP4 (0.41) | SCN9ACYP3A4CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |