Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435438 | 0.89 | PRKCA (0.37) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL14253899 | 0.87 | NR1I2 (0.44) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL14253893 | 0.84 | PRKCA (0.40) | PRKCAMMP12SCN9AALDH1A1NPSR1 | |
| SCHEMBL14253454 | 0.83 | PRKCA (0.46) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL3574582 | 0.82 | PRKCA (0.44) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL4825561 | 0.82 | SCN9A (0.45) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL3577991 | 0.81 | SCN9A (0.47) | PRKCAMMP12SCN9ABRD4CREBBP | |
| SCHEMBL13841666 | 0.79 | ALDH1A1 (0.43) | PRKCAMMP12SCN9AALDH1A1NPSR1 | |
| SCHEMBL3242888 | 0.79 | ALDH1A1 (0.43) | PRKCAMMP12SCN9AALDH1A1NPSR1 | |
| SCHEMBL804192 | 0.78 | PRKCA (0.44) | PRKCAMMP12SCN9ACYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |