Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 5/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.61 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12123619 | 0.89 | ALDH1A1 (0.97) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL7388040 | 0.88 | KMT2A (0.60) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL492212 | 0.86 | HRH3 (0.77) | ALDH1A1LMNAMAPTHRH3THRB | |
| SCHEMBL7926935 | 0.85 | POLB (0.65) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL7375128 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL19286931 | 0.84 | POLB (0.66) | ALDH1A1LMNAMAPTKMT2AHTT | |
| Hydrochloric Acid SCHEMBL7372372 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL7378554 | 0.83 | HRH3 (0.58) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL7375822 | 0.83 | HRH3 (0.58) | ALDH1A1LMNAMAPTKMT2AHTT | |
| Hydrochloric Acid SCHEMBL7375876 | 0.82 | TSHR (0.60) | ALDH1A1LMNAMAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098090-A2 | TREATMENT OF HYPERPROLIFERATIVE DISEASES WITH N-OXIDES OF ESTROGEN RECEPTOR MODULATORS | NOVACEA, INC. (US) | 2007-08-30 | — | — | WO | disclosed |