Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711738 | 0.85 | POLB (0.35) | POLBMAPK1PGDABCB1TDP1 | |
| SCHEMBL14435464 | 0.83 | POLB (0.37) | POLBMAPK1PGDTDP1 | |
| SCHEMBL14435475 | 0.79 | ALDH1A1 (0.36) | TDP1ALDH1A1HPGD | |
| SCHEMBL709956 | 0.73 | LMNA (0.33) | ALDH1A1HPGD | |
| SCHEMBL3026389 | 0.73 | POLB (0.42) | POLBMAPK1PGDABCB1TDP1 | |
| SCHEMBL14435462 | 0.71 | — | — | |
| SCHEMBL718786 | 0.70 | POLB (0.34) | POLBMAPK1PGDTDP1 | |
| SCHEMBL3024600 | 0.70 | LMNA (0.44) | POLBMAPK1PGDABCB1TDP1 | |
| SCHEMBL711739 | 0.70 | ABCB1 (0.33) | POLBMAPK1ABCB1HPGD | |
| SCHEMBL3024742 | 0.70 | POLB (0.40) | POLBMAPK1PGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007094683-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | disclosed |