Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | SAT1 | P21673 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000699 | 0.81 | — | — | |
| SCHEMBL5228250 | 0.80 | TDP1 (0.46) | TDP1SAT1CYP2D6ALDH1A1EPHX1 | |
| SCHEMBL13136202 | 0.78 | SAT1 (0.45) | TDP1SAT1TSHRALDH1A1EPHX1 | |
| SCHEMBL30973705 | 0.78 | CA5A (0.41) | TDP1TSHRALDH1A1CYP3A4CA12 | |
| SCHEMBL4424894 | 0.77 | — | — | |
| SCHEMBL3854192 | 0.76 | TDP1 (0.52) | TDP1SAT1CYP2D6ALDH1A1EPHX1 | |
| SCHEMBL175234 | 0.75 | TDP1 (0.46) | TDP1TSHRALDH1A1CYP3A4CA2 | |
| SCHEMBL3314730 | 0.74 | TDP1 (0.50) | TDP1SAT1CYP2D6EPHX1HDAC3 | |
| SCHEMBL4697448 | 0.74 | TDP1 (0.83) | TDP1CYP2D6ALDH1A1EPHX1CYP3A4 | |
| SCHEMBL13999422 | 0.74 | TDP1 (0.83) | TDP1CYP2D6ALDH1A1EPHX1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096393-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |