Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602707 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1SLC22A2SLC22A1 | |
| SCHEMBL9729528 | 0.80 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1SLC22A2SLC22A1 | |
| SCHEMBL20663566 | 0.79 | TDP1 (0.45) | LMNATSHRCYP2C19BLMPMP22 | |
| SCHEMBL14436497 | 0.76 | MAPT (0.33) | KMT2A | |
| SCHEMBL19919953 | 0.75 | DPP7 (0.47) | ALDH1A1LMNAMAPK1SLC22A2SLC22A1 | |
| SCHEMBL15889841 | 0.74 | TDP1 (0.54) | ALDH1A1MAPK1HPGDCYP1A2CYP2C9 | |
| SCHEMBL3319762 | 0.74 | CYP1A2 (0.44) | ALDH1A1MAPK1CYP2C19HPGDKDM4E | |
| SCHEMBL35602 | 0.73 | — | — | |
| SCHEMBL3319764 | 0.73 | CYP1A2 (0.47) | ALDH1A1LMNAMAPK1SLC22A2SLC22A1 | |
| SCHEMBL3634362 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPK1SLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096393-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2007-08-30 | — | — | WO | disclosed |