SCHEMBL14435592

SCHEMBL14435592

COc1ccc(/N=N/C2=C(O)c3ccccc3C2=O)c(OC)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.63
RAB9A P51151 6/20 0.63
ALDH1A1 P00352 5/20 0.63
KMT2A Q03164 5/20 0.63
NPC1 O15118 5/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
PKM P14618 2/20 0.63
MEN1 O00255 4/20 0.54
PSMD14 O00487 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
LMNA P02545 2/20 0.44
NFKB1 P19838 1/20 0.44
CASP3 P42574 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14435593 0.81 MAPT (0.48) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL12052055 0.75 ALDH1A1 (0.42) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL14434940 0.74 KMT2A (0.48) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3287372 0.71 CYP19A1 (0.53) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3287376 0.71 CYP19A1 (0.53) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3304010 0.67 PHLPP2 (0.48) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3309127 0.67 PHLPP2 (0.63) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3304015 0.67 PHLPP2 (0.48) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL3309129 0.67 PHLPP2 (0.63) MAPTRAB9AALDH1A1KMT2ANPC1
SCHEMBL9017464 0.67 SENP3 (0.52) MAPTRAB9AALDH1A1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007093506-A2 O,P-DIALKOXY-PHENYL-AZOMETAL COMPLEX DYES AND THEIR USE IN OPTICAL LAYERS FOR OPTICAL DATA RECORDING CLARIANT INTERNATIONAL LTD (CH) 2007-08-23 WO disclosed